Oxford Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it tries to restore itself to normal before the harm was achieved. Satterwhite Chiropractic is never shocked at what the body can do! Satterwhite Chiropractic sees its Oxford chiropractic care as the body’s partner in healing especially when spine pain is an issue. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value by interrupting the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to the cellular level via autophagy, the natural process via which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin enhanced autophagy and reduced the degradation of the disc’s extracellular matrix (technically indicated by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin inhibits intervertebral disc degeneration by stimulating autophagy. (3) Wow. Satterwhite Chiropractic is inspired by this research to see just how well melatonin can perform for Oxford back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is such a common malady seen at Satterwhite Chiropractic making positive news like this quite exciting. A new study stated that melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin reduced the inflammatory cell collection and decreased the release of connected inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin disrupted the IL-1B feedback loop, researchers suggested that melatonin may provide the healing process of intervertebral discs after damage was already present. (1) Satterwhite Chiropractic continues following the new research on the role inflammation plays in Oxford disc degeneration and melatonin’s role in combatting it.

INFLAMMATION AND MELATONIN

The importance of melatonin in helping to slow or stop painful conditions due to inflammation is growing. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other mechanisms is quite suitable. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin influences the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific effect on inflammation and disc degeneration is most interesting to Satterwhite Chiropractic and our Oxford back pain patients.

CONTACT Satterwhite Chiropractic

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management manages disc degeneration for relief of chronic low back pain in her patient.

Schedule your Oxford chiropractic appointment with Satterwhite Chiropractic today. We can talk about the role inflammation plays in your back pain experience and how melatonin may address the related disc degeneration.

 
Satterwhite Chiropractic shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."